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In order to fill specific gaps in our knowledge related to how in utero, early postnatal and pubertal environmental exposures impact the development of the mammary gland at the cellular, molecular, organ and population level to influence future breast cancer risk it is necessary to adopt a multidisciplinary research approach. Furthermore, it is critically important that the design of the research projects be responsive community based, faith based, and advocacy organizations that are concerned with breast cancer. Finally, it is also important to develop and implement strategies to translate the scientific findings of the research into information for the public and policy makers. We believe that Michigan State University which has a strong record in research in mammary gland biology and breast cancer, environmental toxicology, epidemiology of breast cancer and community outreach is excellently positioned to accomplish these goals.

Multidisciplinary Nature and Expertise of Co-Investigators in
Collaborative Research Project 1

Investigators Degree Expertise
Sandra Z. Haslam,
PhD
Endocrinology/Tumor Biology Hormonal regulation of normal mammary gland development
Susan E. Conrad,
PhD
Biochemistry/Molecular Biology Cell cycle regulation and estrogen responsiveness in breast cancer
Richard Miksicek,
PhD
Biochemistry/Molecular Endocrinology Molecular mechanisms of steroid hormone action in breast cancer
Richard Schwartz,
PhD
Biochemistry/Molecular Biology Molecular mechanisms of transcriptional regulation by C/EBP_
Chengfeng Yang, M.D., Ph.D Molecular Toxicology Cancer Prevention and Chemical carcinogenesis studies
Karl Olson,
PhD
Pharmacology/Molecular Biology Molecular mechanisms of type II diabetes


Community Advocates


Investigators Degree Expertise
Paulette Valliere,
PhD
Manager, Operations Unit
Michigan Department of Community Health
Breast and cervical cancer screening project for low income residents of Michigan
Latecia Matthews,
BS
Project Specialist
Faith Access to Community Economic Development
Health and human behavior; health education. Health access and education for the African American community in Flint, Michigan.
Becky Cwiek, CPhT, BS Health care President, Michigan Breast Cancer Coalition
Judy Bearup   Office Manager and assistant to the president, Michigan Environmental Council
Vicki Rakowski,
RN
Executive Vice-President for Medical Activities, American Cancer Society, Great Lakes Division Breast cancer advocacy and education.


Multidisciplinary Nature and Expertise of Co-Investigators and Community Advocates in the Community Outreach and Translation Core

Investigators Degree Expertise
Charles Atkin,
PhD
Mass Communication Design and implementation of communication strategies.
Pam Whitten,
PhD
Telecommunication Telemedicine and webpage design and evaluation.
Sandi Smith, Communication Media content analysis researcher,
persuasive message designer, and focus group moderator.

Kami Silk,
PhD

Communication Development of educational materials to present health risk information to target audiences; the role of health literacy and numeracy in audience
understanding of risk messages, particularly among low income segments of the population.
Charles Salmon,
PhD
Advertising Health campaigns, public opinion analysis, and issues management.
Janet Osuch,
MD, MS
Surgery, Epidemiology Breast cancer; interpreting scientific issues for the lay public; National Media Spokesperson for the American Cancer Society for breast cancer.
William Donohue,
PhD
Communication Outreach research and practice applied to youth and families in Michigan, focusing on the prevention of risky behavior during childhood and adolescence.

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